An intersting topic. AFAIK, there have been no recalls, software updates, known issues, etc. This is remarkable for any once-every-6-years "all new" variant, let alone a brand new "clean sheet" design/platform/factory. The only thing that I am aware of that has been a consistent complaint is the vibration rattle near the A-pillar, which apparently has a known fix (and that I plan on addressing at the first oil change).
Far too soon to make any pronouncements on long term reliability, but all the initial data seems to be positive.
Honestly, my view is that "zero defects" is a dumb goal because it leads to delays and excessive conservatism. I would MUCH rather have the policy of "ship it sooner, but REALLY take care of early adopters who experience hassles."
I think this is another manifestation of Honda philosophy somewhat shooting themselves in the foot.