there are many inherent problems with running 100% methanol, namely safety as it boils at 148F. but that aside, you will lose a good amount of torque generated by the steam effect on the power stroke of the engine cycle leading to more torque. (Same principle that Steam engines were designed around) . Also at 100% methanol you are basically running a dual fuel engine.
however many people do, I do in my GN, because Methanol has a kick ass flame travel speed especially in a rich environment. The flame travel speeds even at stoich are better than gasoline by far which is nice because you do more positive work when more of your mixture burns at TDC. On top of that it is making use of space by adding heat while still offering a better cooling effect than gasoline.
I run a Fogger style setup, for direct port methanol injection. i use 150cc nozzles at each runner. But thats a 3.8L v6. When I had my Z, I ran a single 500cc nozzle at 100% and a 700cc nozzle at 50/50.
Is it worth 100%, you'll make more power but you have to be alot more conciseness, if you have the cheap plastic line, you must check it for failure often as it eats away at it. Also you might on hot days where engine bay temps go above 150F, get nozzle drip and cause the car to run rough at idle due to increase in line pressure. Lastly that tune better be dead on and have a fail safe light or map change if the flow changes.
just my 2cents, I do it, but the GN is only a 1/4 mile car.