MiamieNeSeX,
What kind of places are you looking for?
I-Drive has pointe orlando with a couple clubs but not my favorite place to go. I-Drive intersects with Sandlake and there are some nice restaurants around there, Samba room(turns into a salsa place at night), Seasons 52, Moon Fish Grill(same people that own charlies, excellent seafood and steaks) cafe tu tu tango, tapas size dishes with cuisine from around the world, cool place. City walk has Emerils, pain to get a reservation I hear, and there are bars and clubs in there, Groove, Bob Marley's, Pat O Brians, Motown Cafe, mix of tourists and locals. Downtown has a bunch of bars and clubs mostly locals. Zinc - little more upscale, plays house/techno, nice place, rhtymn and flow is about the same. Wallstreet, six bars, has a band in the street and six clubs all slightly different, hip hop or top 40, all kinds go there , room 39 plays 80's. Tabu large dance club, typically a younger crowd. There is also Blue Matini at the millenium mall, mix of old and young people some rich...some pretending to be rich...ok once in a while. Personally I prefer downtown as I can walk to several places that are different from each other. Oh and there is Roxy's too which is not bad but won't get busy until about 11:30 or 12, thats by itself as well.
Hope that helps, if you want more specific recommendations let me know.
See you Sunday,
Carl